Gene interactions and pathways from curated databases and text-mining
CASP8: top 25 interacting genes (chr2:202125258-202152432)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP8-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP8, not among the Top 25
Other genes interacting with CASP8. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ABCC6 ▸ ABCD1 ▸ ABL1 ▸ ACAD8 ▸ ACHE ▸ ACIN1 ▸ ACSM3 ▸
ACTA2 ▸ ACTG2 ▸ ACTL6A ▸ ADCYAP1 ▸ ADH5 ▸ ADIPOQ ▸ ADM ▸
AFP ▸ AGTR1 ▸ AHSA1 ▸ AIM2 ▸ AIP ▸ AKT3 ▸ ALB ▸
ALK ▸ ALPI ▸ ANG ▸ ANGPT1 ▸ ANGPT2 ▸ ANP32A ▸ ANXA1 ▸
ANXA5 ▸ ANXA6 ▸ APAF1 ▸ APC ▸ APEH ▸ APEX1 ▸ APIP ▸
APOB ▸ APOBEC3D ▸ APOE ▸ APP ▸ AR ▸ ARC ▸ ARHGDIA ▸
ARID1A ▸ ARSA ▸ ARSK ▸ ASIP ▸ ATAD3A ▸ ATF2 ▸ ATF5 ▸
ATG3 ▸ ATG4D ▸ ATG5 ▸ ATM ▸ ATN1 ▸ ATP5O ▸ BACE1 ▸
BAD ▸ BAG3 ▸ BCAP31 ▸ BCL2L12 ▸ BCL3 ▸ BCL5 ▸ BCL6 ▸
BCL9 ▸ BCR ▸ BDNF ▸ BECN1 ▸ BFAR ▸ BID ▸ BIRC2 ▸
BIRC3 ▸ BIRC5 ▸ BIRC6 ▸ BIRC7 ▸ BIRC8 ▸ BLM ▸ BMP1 ▸
BMP10 ▸ BMP15 ▸ BMP2 ▸ BMP3 ▸ BMP4 ▸ BMP5 ▸ BMP6 ▸
BMP7 ▸ BNIP3 ▸ BNIP3L ▸ BOC ▸ BRCA1 ▸ C22orf29 ▸ CA2 ▸
CA8 ▸ CALB1 ▸ CALM3 ▸ CALML3 ▸ CALR ▸ CAPN1 ▸ CAPN10 ▸
CAPN11 ▸ CAPN12 ▸ CAPN13 ▸ CAPN14 ▸ CAPN15 ▸ CAPN2 ▸ CAPN3 ▸
CAPN5 ▸ CAPN6 ▸ CAPN7 ▸ CAPN8 ▸ CAPN9 ▸ CAPNS1 ▸ CARD10 ▸
CARD11 ▸ CARD14 ▸ CARD16 ▸ CARD17 ▸ CARD18 ▸ CARD6 ▸ CARD8 ▸
CARD9 ▸ CASP1 ▸ CASP10 ▸ CASP12 ▸ CASP14 ▸ CASP16 ▸ CASP2 ▸
CASP3 ▸ CASP4 ▸ CASP5 ▸ CASP6 ▸ CASP7 ▸ CASP8AP2 ▸ CASP9 ▸
CAST ▸ CAT ▸ CCDC88A ▸ CCK ▸ CCL19 ▸ CCL2 ▸ CCNC ▸
CCND1 ▸ CCNH ▸ CCR1 ▸ CCR10 ▸ CCR2 ▸ CCR3 ▸ CCR4 ▸
CCR5 ▸ CCR6 ▸ CCR7 ▸ CCR8 ▸ CCR9 ▸ CD14 ▸ CD2 ▸
CD247 ▸ CD3D ▸ CD3E ▸ CD3G ▸ CD4 ▸ CD40 ▸ CD47 ▸
CD79A ▸ CD79B ▸ CD8A ▸ CD8B ▸ CDA ▸ CDC42 ▸ CDC6 ▸
CDC73 ▸ CDCA5 ▸ CDH1 ▸ CDK1 ▸ CDK10 ▸ CDK11A ▸ CDK11B ▸
CDK12 ▸ CDK13 ▸ CDK14 ▸ CDK15 ▸ CDK16 ▸ CDK17 ▸ CDK18 ▸
CDK19 ▸ CDK2 ▸ CDK20 ▸ CDK3 ▸ CDK4 ▸ CDK5 ▸ CDK6 ▸
CDK7 ▸ CDK8 ▸ CDK9 ▸ CDKN1A ▸ CENPK ▸ CEP104 ▸ CEP112 ▸
CEP120 ▸ CEP128 ▸ CEP135 ▸ CEP152 ▸ CEP164 ▸ CEP170 ▸ CEP19 ▸
CEP192 ▸ CEP250 ▸ CEP290 ▸ CEP350 ▸ CEP41 ▸ CEP44 ▸ CEP55 ▸
CEP57 ▸ CEP63 ▸ CEP68 ▸ CEP70 ▸ CEP72 ▸ CEP76 ▸ CEP78 ▸
CEP85 ▸ CEP89 ▸ CEP95 ▸ CEP97 ▸ CFL1 ▸ CFLAR ▸ CFTR ▸
CHD3 ▸ CHUK ▸ CIB1 ▸ CISH ▸ CLIP3 ▸ CLTC ▸ COL11A1 ▸
COL11A2 ▸ COL1A1 ▸ COL1A2 ▸ COL2A1 ▸ COL3A1 ▸ COL4A1 ▸ COL4A3 ▸
COL4A4 ▸ COL4A5 ▸ COL4A6 ▸ COL5A1 ▸ COL5A2 ▸ COL6A1 ▸ COL6A2 ▸
COL6A3 ▸ COL7A1 ▸ COP ▸ COPS6 ▸ CPA1 ▸ CPOX ▸ CRADD ▸
CREB1 ▸ CREB3 ▸ CREB5 ▸ CRK ▸ CRYAB ▸ CSE ▸ CSF1 ▸
CSF2 ▸ CSF3 ▸ CTNNB1 ▸ CTNNBL1 ▸ CTNND1 ▸ CTR9 ▸ CTRL ▸
CTSB ▸ CTSD ▸ CTSL ▸ CUL1 ▸ CUL3 ▸ CXCL13 ▸ CXCL17 ▸
CXCL9 ▸ CYCS ▸ CYR61 ▸ DAP3 ▸ DAPK2 ▸ DAXX ▸ DDIT3 ▸
DDX28 ▸ DEDD2 ▸ DERL1 ▸ DES ▸ DFFA ▸ DFFB ▸ DHCR24 ▸
DIABLO ▸ DIDO1 ▸ DISC1 ▸ DISC2 ▸ DLG1 ▸ DNAJC5 ▸ DNAJC7 ▸
DNASE1 ▸ DNASE2 ▸ DNTT ▸ DST ▸ DYRK1A ▸ E2F1 ▸ E2F2 ▸
E2F3 ▸ EDA2R ▸ EDNRA ▸ EEF1A2 ▸ EGF ▸ EGFR ▸ EHMT1 ▸
EIF2AK2 ▸ EIF2S1 ▸ EIF3S10 ▸ EIF4A1 ▸ EIF4G1 ▸ EIF4G2 ▸ EIF4G3 ▸
ELAVL1 ▸ EML2 ▸ EMP1 ▸ EMP2 ▸ EMP3 ▸ ENDOG ▸ EP300 ▸
EPHB2 ▸ EPO ▸ EPX ▸ ERVK-6 ▸ ETS1 ▸ ETS2 ▸ EZR ▸
FADD ▸ FAF1 ▸ FAM168B ▸ FASLG ▸ FGF2 ▸ FHIT ▸ FIS1 ▸
FOS ▸ FOXO1 ▸ FOXO3 ▸ FOXP3 ▸ FUT1 ▸ GAL ▸ GATA1 ▸
GDNF ▸ GHSR ▸ GJA1 ▸ GLI1 ▸ GNA11 ▸ GNRH1 ▸ GP2 ▸
GP5 ▸ GP6 ▸ GP9 ▸ GPI ▸ GPX1 ▸ GPX3 ▸ GRAP2 ▸
GRB10 ▸ GRB14 ▸ GRB2 ▸ GRB7 ▸ GRIA1 ▸ GRK1 ▸ GRK4 ▸
GRK5 ▸ GRK6 ▸ GRK7 ▸ GRP ▸ GSK3B ▸ GSN ▸ GSTT1 ▸
GUCY2D ▸ GYS1 ▸ GYS2 ▸ GZMB ▸ H2AFX ▸ HCLS1 ▸ HDAC1 ▸
HDAC2 ▸ HDAC4 ▸ HDAC6 ▸ HGF ▸ HIF1A ▸ HIP1 ▸ HIPK2 ▸
HIST1H4A ▸ HIST2H2BE ▸ HLA-DRB1 ▸ HMGB1 ▸ HMGCR ▸ HMOX1 ▸ HNRNPH2 ▸
HPR ▸ HRD ▸ HRK ▸ HSF1 ▸ HSP90AA1 ▸ HSPA5 ▸ HSPB1 ▸
HSPD1 ▸ HTRA1 ▸ HTRA2 ▸ HTRA3 ▸ HTRA4 ▸ HTT ▸ HUNK ▸
IAPP ▸ IARS ▸ ICAM1 ▸ ID3 ▸ IDO1 ▸ IFI27 ▸ IFI44 ▸
IFIH1 ▸ IFNA2 ▸ IFNB1 ▸ IFNG ▸ IFT57 ▸ IGF1 ▸ IGF1R ▸
IGF2 ▸ IGFBP3 ▸ IKBKB ▸ IKBKG ▸ IL10 ▸ IL11 ▸ IL13 ▸
IL15 ▸ IL16 ▸ IL18 ▸ IL19 ▸ IL1A ▸ IL1B ▸ IL1R1 ▸
IL1R2 ▸ IL1RN ▸ IL2 ▸ IL20 ▸ IL21 ▸ IL22 ▸ IL24 ▸
IL25 ▸ IL26 ▸ IL27 ▸ IL3 ▸ IL31 ▸ IL32 ▸ IL33 ▸
IL34 ▸ IL37 ▸ IL4 ▸ IL5 ▸ IL6 ▸ IL7 ▸ IL8 ▸
IL9 ▸ ING1 ▸ INS ▸ IQGAP1 ▸ IRF1 ▸ IRF2 ▸ IRF3 ▸
IRF4 ▸ IRF5 ▸ IRF6 ▸ IRF7 ▸ IRF8 ▸ IRF9 ▸ IRS1 ▸
IRS4 ▸ ITCH ▸ ITGA2 ▸ ITGAV ▸ ITGB1 ▸ ITGB3 ▸ ITIH4 ▸
JAK1 ▸ JAK2 ▸ JAK3 ▸ JUN ▸ KARS ▸ KDR ▸ KHDRBS1 ▸
KLF4 ▸ KLK3 ▸ KLKB1 ▸ KMT2A ▸ KRR1 ▸ KRT18 ▸ LAT ▸
LEO1 ▸ LEP ▸ LGALS1 ▸ LMNB1 ▸ LMNB2 ▸ LPA ▸ LRP1 ▸
LRRC59 ▸ LY96 ▸ LYN ▸ LYPLA1 ▸ MAGT1 ▸ MALT1 ▸ MAP1LC3A ▸
MAP1LC3B ▸ MAP2 ▸ MAP2K1 ▸ MAP2K2 ▸ MAP2K3 ▸ MAP2K4 ▸ MAP2K5 ▸
MAP2K6 ▸ MAP2K7 ▸ MAP3K1 ▸ MAP3K14 ▸ MAP3K7 ▸ MAP4K4 ▸ MAPK1 ▸
MAPK10 ▸ MAPK11 ▸ MAPK12 ▸ MAPK13 ▸ MAPK14 ▸ MAPK15 ▸ MAPK3 ▸
MAPK4 ▸ MAPK6 ▸ MAPK7 ▸ MAPK8 ▸ MAPK9 ▸ MAPT ▸ MCL1 ▸
MDM2 ▸ ME2 ▸ MED1 ▸ MED12 ▸ MED13 ▸ MED14 ▸ MED15 ▸
MED17 ▸ MED21 ▸ MED23 ▸ MED24 ▸ MED25 ▸ MED26 ▸ MED4 ▸
MED6 ▸ MED7 ▸ MED8 ▸ MEFV ▸ MEPE ▸ MET ▸ MICE ▸
MIF ▸ MLYCD ▸ MME ▸ MMP1 ▸ MMP10 ▸ MMP11 ▸ MMP12 ▸
MMP13 ▸ MMP14 ▸ MMP15 ▸ MMP16 ▸ MMP17 ▸ MMP19 ▸ MMP2 ▸
MMP20 ▸ MMP21 ▸ MMP24 ▸ MMP25 ▸ MMP26 ▸ MMP27 ▸ MMP28 ▸
MMP3 ▸ MMP7 ▸ MMP8 ▸ MMP9 ▸ MPST ▸ MPZ ▸ MSC ▸
MSN ▸ MST1 ▸ MST1R ▸ MT3 ▸ MT4 ▸ MTA1 ▸ MTA2 ▸
MTA3 ▸ MTOR ▸ MUC1 ▸ MUC12 ▸ MUC13 ▸ MUC15 ▸ MUC16 ▸
MUC17 ▸ MUC19 ▸ MUC2 ▸ MUC20 ▸ MUC21 ▸ MUC22 ▸ MUC4 ▸
MUC6 ▸ MUC7 ▸ MUC8 ▸ MYC ▸ MYLIP ▸ MYO9A ▸ NA ▸
NAB1 ▸ NAB2 ▸ NACA ▸ NAIP ▸ NANOG ▸ NANOS2 ▸ NCL ▸
NEFH ▸ NFKBIA ▸ NGF ▸ NLRC4 ▸ NLRC5 ▸ NLRP1 ▸ NLRP3 ▸
NLRP5 ▸ NLRP7 ▸ NOD1 ▸ NOD2 ▸ NOL3 ▸ NOS1 ▸ NOS2 ▸
NOS3 ▸ NOX1 ▸ NOX3 ▸ NOX4 ▸ NOX5 ▸ NPM1 ▸ NPPA ▸
NPS ▸ NPY6R ▸ NR0B1 ▸ NR1H4 ▸ NTF3 ▸ NTF4 ▸ NTN1 ▸
NUAK1 ▸ NUCB1 ▸ NUCB2 ▸ NUP153 ▸ NUP210 ▸ NUP214 ▸ NUP43 ▸
NUP62 ▸ ODC1 ▸ OTUD7B ▸ P2RX7 ▸ PAEP ▸ PAF1 ▸ PAK1 ▸
PAK2 ▸ PAN2 ▸ PAN3 ▸ PANX1 ▸ PARG ▸ PARK2 ▸ PARK7 ▸
PC ▸ PCBD1 ▸ PCNA ▸ PCYT1A ▸ PDCD1 ▸ PDCD10 ▸ PDCD11 ▸
PDCD2 ▸ PDCD4 ▸ PDCD5 ▸ PDCD6 ▸ PDCD7 ▸ PDGFB ▸ PDIA6 ▸
PDLIM7 ▸ PEA15 ▸ PGF ▸ PGP ▸ PI3 ▸ PIAS1 ▸ PICALM ▸
PIDD ▸ PIDD1 ▸ PIK3CA ▸ PIK3R1 ▸ PIN1 ▸ PLA2G4B ▸ PLCG1 ▸
PLD1 ▸ PLD2 ▸ PLD3 ▸ PLD4 ▸ PLD5 ▸ PLD6 ▸ PLEC ▸
PLIN4 ▸ PLK1 ▸ PLOD2 ▸ PMEL ▸ PML ▸ PNPLA2 ▸ POLDIP2 ▸
PPARA ▸ PPARG ▸ PPP1R3A ▸ PPP2CA ▸ PPP2R1A ▸ PPP2R2B ▸ PPT1 ▸
PRDX2 ▸ PRG2 ▸ PRG3 ▸ PRG4 ▸ PRKAA1 ▸ PRKAA2 ▸ PRKAB1 ▸
PRKAB2 ▸ PRKACB ▸ PRKACG ▸ PRKAG1 ▸ PRKAG2 ▸ PRKAR1A ▸ PRKAR1B ▸
PRKAR2A ▸ PRKAR2B ▸ PRKCA ▸ PRKCD ▸ PRKCG ▸ PRKCI ▸ PRKDC ▸
PRNP ▸ PSEN1 ▸ PSENEN ▸ PSMB9 ▸ PSMD10 ▸ PTBP1 ▸ PTCH1 ▸
PTEN ▸ PTGS2 ▸ PTHLH ▸ PTK2 ▸ PTPN11 ▸ PTPN13 ▸ PTPN6 ▸
PTX3 ▸ PTX4 ▸ PXN ▸ PYCARD ▸ QRICH1 ▸ QRICH2 ▸ RAB10 ▸
RAB5A ▸ RAC1 ▸ RAC2 ▸ RAC3 ▸ RAD1 ▸ RAD17 ▸ RAD18 ▸
RAD21 ▸ RAD50 ▸ RAD51 ▸ RAD52 ▸ RAF1 ▸ RALBP1 ▸ RALGDS ▸
RANBP2 ▸ RARA ▸ RASA1 ▸ RB1 ▸ RBBP4 ▸ RBBP7 ▸ RBL2 ▸
RENBP ▸ RHO ▸ RIPK1 ▸ RIPK2 ▸ RIPK3 ▸ RIPK4 ▸ RNF135 ▸
RNF19A ▸ RNF34 ▸ ROCK1 ▸ ROCK2 ▸ RPS27 ▸ RPS27L ▸ RRAS ▸
RUNX3 ▸ S100A12 ▸ SAA1 ▸ SATB1 ▸ SDS ▸ SEC14L2 ▸ SEPT4 ▸
SERP2 ▸ SERPINA1 ▸ SERPINB9 ▸ SERPINF1 ▸ SETBP1 ▸ SETD2 ▸ SHC1 ▸
SIVA1 ▸ SKP1 ▸ SLC17A5 ▸ SLC9A1 ▸ SLCO6A1 ▸ SLPI ▸ SMAD3 ▸
SMAD4 ▸ SMAD7 ▸ SMARCA2 ▸ SMARCA4 ▸ SMARCB1 ▸ SMARCC1 ▸ SMARCC2 ▸
SMARCD1 ▸ SMARCD2 ▸ SMARCE1 ▸ SMPD1 ▸ SMPD2 ▸ SNAP25 ▸ SOAT1 ▸
SOD1 ▸ SOD2 ▸ SOD3 ▸ SORBS1 ▸ SP1 ▸ SPARC ▸ SPP1 ▸
SQSTM1 ▸ SRC ▸ SREBF1 ▸ SREBF2 ▸ STAT1 ▸ STAT3 ▸ STC1 ▸
STK24 ▸ STS ▸ STSP1 ▸ STX1A ▸ STX2 ▸ SUB1 ▸ SYF2 ▸
SYK ▸ SYT1 ▸ TAC1 ▸ TAC3 ▸ TAC4 ▸ TARDBP ▸ TAT ▸
TCF12 ▸ TCF15 ▸ TCF19 ▸ TCF20 ▸ TCF21 ▸ TCF23 ▸ TCF24 ▸
TCF25 ▸ TCF3 ▸ TCF4 ▸ TCF7 ▸ TCHP ▸ TET1 ▸ TET2 ▸
TET3 ▸ TFAP2A ▸ TFCP2 ▸ TGFB1 ▸ TGFB3 ▸ TGM2 ▸ THBS1 ▸
TICAM2 ▸ TIMP3 ▸ TLR1 ▸ TLR10 ▸ TLR2 ▸ TLR3 ▸ TLR4 ▸
TLR5 ▸ TLR6 ▸ TLR7 ▸ TLR8 ▸ TLR9 ▸ TMED7 ▸ TNFAIP3 ▸
TNFRSF10A ▸ TNFRSF10B ▸ TNFRSF1A ▸ TNFRSF1B ▸ TNFRSF25 ▸ TNFRSF8 ▸ TNFSF12 ▸
TNFSF14 ▸ TOP1 ▸ TOPORS ▸ TRA ▸ TRAF1 ▸ TRAF2 ▸ TRAF3 ▸
TRAF4 ▸ TRAF5 ▸ TRAF6 ▸ TRAF7 ▸ TRIM25 ▸ TRIM28 ▸ TSC22D3 ▸
TUBA1A ▸ TUBA1C ▸ TUBB ▸ TXN ▸ TYR ▸ UBB ▸ UBC ▸
UBE2D1 ▸ UBE2L3 ▸ UBR5 ▸ UCN ▸ UCP2 ▸ UPK3B ▸ USP2 ▸
USP54 ▸ VCP ▸ VDAC1 ▸ VDAC2 ▸ VDAC3 ▸ VEGFA ▸ VIM ▸
VIMP ▸ VIP ▸ WAS ▸ WDR61 ▸ WNK1 ▸ WNT1 ▸ WNT3A ▸
XAF1 ▸ XIAP ▸ XRCC6 ▸ YES1 ▸ ZGLP1 ▸
Data information
Please see the Gene Interactions Track Manual.