Gene interactions and pathways from curated databases and text-mining
CASP3: top 25 interacting genes (chr4:185548849-185570601)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only CASP3-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
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Less-frequently mentioned interactions with CASP3, not among the Top 25
Other genes interacting with CASP3. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

ABCC6 ▸ ABCD1 ▸ ABL1 ▸ ACAD8 ▸ ACHE ▸ ACIN1 ▸ ACR ▸
ACSM3 ▸ ACTA1 ▸ ACTL6A ▸ ACVR1C ▸ ADCYAP1 ▸ ADH5 ▸ ADIPOQ ▸
ADM ▸ AFP ▸ AGTR1 ▸ AHSA1 ▸ AIFM1 ▸ AIM2 ▸ AIP ▸
AKAP8 ▸ AKT3 ▸ ALB ▸ ALK ▸ ALPI ▸ ANG ▸ ANGPT1 ▸
ANGPT2 ▸ ANGPT4 ▸ ANP32A ▸ ANXA1 ▸ ANXA5 ▸ ANXA6 ▸ APAF1 ▸
APC ▸ APEH ▸ APEX1 ▸ APIP ▸ APOB ▸ APOBEC3D ▸ APOE ▸
APP ▸ AR ▸ ARC ▸ ARHGDIA ▸ ARHGDIB ▸ ARID1A ▸ ARSA ▸
ARSK ▸ ASIP ▸ ATF2 ▸ ATF5 ▸ ATG3 ▸ ATG4D ▸ ATG5 ▸
ATM ▸ ATN1 ▸ ATP5O ▸ BACE1 ▸ BAD ▸ BAG3 ▸ BCAP31 ▸
BCAR1 ▸ BCL2L12 ▸ BCL3 ▸ BCL5 ▸ BCL6 ▸ BCL9 ▸ BCR ▸
BDNF ▸ BECN1 ▸ BID ▸ BIRC2 ▸ BIRC3 ▸ BIRC4 ▸ BIRC5 ▸
BIRC6 ▸ BIRC7 ▸ BIRC8 ▸ BLM ▸ BMP1 ▸ BMP10 ▸ BMP15 ▸
BMP2 ▸ BMP3 ▸ BMP4 ▸ BMP5 ▸ BMP6 ▸ BMP7 ▸ BMX ▸
BNIP3 ▸ BOC ▸ BRCA1 ▸ C22orf29 ▸ CA2 ▸ CA8 ▸ CAD ▸
CALB1 ▸ CALM3 ▸ CALML3 ▸ CALR ▸ CAPN1 ▸ CAPN10 ▸ CAPN11 ▸
CAPN12 ▸ CAPN13 ▸ CAPN14 ▸ CAPN15 ▸ CAPN2 ▸ CAPN3 ▸ CAPN5 ▸
CAPN6 ▸ CAPN7 ▸ CAPN8 ▸ CAPN9 ▸ CAPNS1 ▸ CARD10 ▸ CARD11 ▸
CARD14 ▸ CARD16 ▸ CARD17 ▸ CARD18 ▸ CARD6 ▸ CARD8 ▸ CARD9 ▸
CASP1 ▸ CASP10 ▸ CASP12 ▸ CASP14 ▸ CASP16 ▸ CASP2 ▸ CASP4 ▸
CASP5 ▸ CASP6 ▸ CASP7 ▸ CASP8 ▸ CASP9 ▸ CAST ▸ CAT ▸
CCDC88A ▸ CCK ▸ CCL19 ▸ CCL2 ▸ CCNC ▸ CCND1 ▸ CCNH ▸
CCR1 ▸ CCR10 ▸ CCR2 ▸ CCR3 ▸ CCR4 ▸ CCR5 ▸ CCR6 ▸
CCR7 ▸ CCR8 ▸ CCR9 ▸ CD2 ▸ CD247 ▸ CD4 ▸ CD40 ▸
CD47 ▸ CD79A ▸ CD79B ▸ CD8A ▸ CD8B ▸ CDA ▸ CDC2L1 ▸
CDC2L2 ▸ CDC42 ▸ CDC6 ▸ CDC73 ▸ CDCA5 ▸ CDH1 ▸ CDK1 ▸
CDK10 ▸ CDK11A ▸ CDK11B ▸ CDK12 ▸ CDK13 ▸ CDK14 ▸ CDK15 ▸
CDK16 ▸ CDK17 ▸ CDK18 ▸ CDK19 ▸ CDK2 ▸ CDK20 ▸ CDK3 ▸
CDK4 ▸ CDK5 ▸ CDK6 ▸ CDK7 ▸ CDK8 ▸ CDK9 ▸ CDKN1A ▸
CENPK ▸ CEP104 ▸ CEP112 ▸ CEP120 ▸ CEP128 ▸ CEP135 ▸ CEP152 ▸
CEP164 ▸ CEP170 ▸ CEP19 ▸ CEP192 ▸ CEP250 ▸ CEP290 ▸ CEP350 ▸
CEP41 ▸ CEP44 ▸ CEP55 ▸ CEP57 ▸ CEP63 ▸ CEP68 ▸ CEP70 ▸
CEP72 ▸ CEP76 ▸ CEP78 ▸ CEP85 ▸ CEP89 ▸ CEP95 ▸ CEP97 ▸
CFL1 ▸ CFLAR ▸ CFTR ▸ CHUK ▸ CIB1 ▸ CISH ▸ COP ▸
COPS6 ▸ CPA1 ▸ CPOX ▸ CREB1 ▸ CREB3 ▸ CREB5 ▸ CRK ▸
CRYAB ▸ CSE ▸ CSF1 ▸ CSF2 ▸ CSF3 ▸ CTNNB1 ▸ CTNNBL1 ▸
CTNND1 ▸ CTR9 ▸ CTRL ▸ CTSB ▸ CTSD ▸ CTSL ▸ CTTN ▸
CUL1 ▸ CXCL13 ▸ CXCL9 ▸ CYCS ▸ CYR61 ▸ DAP3 ▸ DAPK2 ▸
DAXX ▸ DBNL ▸ DCTN1 ▸ DDIT3 ▸ DERL1 ▸ DES ▸ DFFA ▸
DFFB ▸ DHCR24 ▸ DIABLO ▸ DIDO1 ▸ DISC1 ▸ DISC2 ▸ DLG1 ▸
DNAJC5 ▸ DNASE1 ▸ DNASE2 ▸ DNTT ▸ DSG1 ▸ DSG2 ▸ DSG3 ▸
DST ▸ DYRK1A ▸ E2F1 ▸ E2F2 ▸ E2F3 ▸ EDNRA ▸ EEF1A2 ▸
EGF ▸ EGFR ▸ EHMT1 ▸ EIF2AK2 ▸ EIF2S1 ▸ EIF3J ▸ EIF3S10 ▸
EIF4A1 ▸ EIF4B ▸ EIF4G1 ▸ EIF4G2 ▸ EIF4G3 ▸ ELANE ▸ ELAVL1 ▸
EML2 ▸ EMP1 ▸ EMP2 ▸ EMP3 ▸ ENDOG ▸ EPHB2 ▸ EPO ▸
EPX ▸ ERVK-6 ▸ ETS1 ▸ ETS2 ▸ FADD ▸ FAF1 ▸ FAM168B ▸
FASLG ▸ FBXW11 ▸ FGF2 ▸ FHIT ▸ FKBP4 ▸ FLT3 ▸ FOS ▸
FOXO1 ▸ FOXO3 ▸ FUK ▸ FUS ▸ FUT1 ▸ GAL ▸ GAS2 ▸
GATA1 ▸ GDNF ▸ GHSR ▸ GJA1 ▸ GLI1 ▸ GMNN ▸ GNA11 ▸
GNRH1 ▸ GORASP1 ▸ GP2 ▸ GP5 ▸ GP6 ▸ GP9 ▸ GPI ▸
GPX1 ▸ GPX3 ▸ GRAP2 ▸ GRB10 ▸ GRB14 ▸ GRB2 ▸ GRB7 ▸
GRIPAP1 ▸ GRP ▸ GSK3B ▸ GSN ▸ GSTT1 ▸ GUCY2D ▸ GYS1 ▸
GYS2 ▸ GZMB ▸ GZMM ▸ H2AFX ▸ HCLS1 ▸ HDAC1 ▸ HDAC2 ▸
HDAC4 ▸ HDAC6 ▸ HEY2 ▸ HGF ▸ HIF1A ▸ HIP1 ▸ HIPK2 ▸
HIST2H2BE ▸ HLA-DRB1 ▸ HMGB1 ▸ HMGCR ▸ HMOX1 ▸ HNRNPA0 ▸ HNRNPD ▸
HNRNPU ▸ HPR ▸ HRAS ▸ HRD ▸ HRK ▸ HSF1 ▸ HSP90AA1 ▸
HSPA5 ▸ HSPB1 ▸ HSPD1 ▸ HTRA1 ▸ HTRA2 ▸ HTRA3 ▸ HTRA4 ▸
HTT ▸ HUNK ▸ IAPP ▸ ICAM1 ▸ ID3 ▸ IDO1 ▸ IFI27 ▸
IFI44 ▸ IFIH1 ▸ IFNA2 ▸ IFNA5 ▸ IFNB1 ▸ IFNG ▸ IFT57 ▸
IGF1 ▸ IGF1R ▸ IGF2 ▸ IGFBP3 ▸ IKBKB ▸ IKBKG ▸ IL10 ▸
IL11 ▸ IL13 ▸ IL15 ▸ IL16 ▸ IL18 ▸ IL19 ▸ IL1A ▸
IL1B ▸ IL1R1 ▸ IL1R2 ▸ IL1RN ▸ IL2 ▸ IL20 ▸ IL21 ▸
IL22 ▸ IL24 ▸ IL25 ▸ IL26 ▸ IL27 ▸ IL3 ▸ IL31 ▸
IL32 ▸ IL33 ▸ IL34 ▸ IL37 ▸ IL4 ▸ IL5 ▸ IL6 ▸
IL7 ▸ IL8 ▸ IL9 ▸ ING1 ▸ INS ▸ IQGAP1 ▸ IRF1 ▸
IRF2 ▸ IRF3 ▸ IRF4 ▸ IRF5 ▸ IRF6 ▸ IRF7 ▸ IRF8 ▸
IRF9 ▸ IRS1 ▸ ITCH ▸ ITIH4 ▸ JAK1 ▸ JAK2 ▸ JAK3 ▸
JUN ▸ KARS ▸ KDR ▸ KEAP1 ▸ KLF4 ▸ KLK3 ▸ KLKB1 ▸
KMT2A ▸ KRT18 ▸ LAT ▸ LEO1 ▸ LEP ▸ LGALS1 ▸ LMNB1 ▸
LMNB2 ▸ LPA ▸ LPAR1 ▸ LPAR3 ▸ LRP1 ▸ LRRC59 ▸ LYN ▸
LYPLA1 ▸ MAGT1 ▸ MAP2 ▸ MAP2K1 ▸ MAP2K2 ▸ MAP2K3 ▸ MAP2K4 ▸
MAP2K5 ▸ MAP2K6 ▸ MAP2K7 ▸ MAP3K1 ▸ MAP3K14 ▸ MAP3K7 ▸ MAP4K1 ▸
MAPK1 ▸ MAPK10 ▸ MAPK11 ▸ MAPK12 ▸ MAPK13 ▸ MAPK14 ▸ MAPK15 ▸
MAPK3 ▸ MAPK4 ▸ MAPK6 ▸ MAPK7 ▸ MAPK8 ▸ MAPK8IP3 ▸ MAPK9 ▸
MAPT ▸ MCL1 ▸ MDC1 ▸ MDM2 ▸ ME2 ▸ MED1 ▸ MED12 ▸
MED13 ▸ MED14 ▸ MED15 ▸ MED17 ▸ MED21 ▸ MED23 ▸ MED24 ▸
MED25 ▸ MED26 ▸ MED4 ▸ MED6 ▸ MED7 ▸ MED8 ▸ MEF2A ▸
MEFV ▸ MET ▸ MICE ▸ MIF ▸ MLH1 ▸ MME ▸ MMP1 ▸
MMP10 ▸ MMP11 ▸ MMP12 ▸ MMP13 ▸ MMP14 ▸ MMP15 ▸ MMP16 ▸
MMP17 ▸ MMP19 ▸ MMP2 ▸ MMP20 ▸ MMP21 ▸ MMP24 ▸ MMP25 ▸
MMP26 ▸ MMP27 ▸ MMP28 ▸ MMP3 ▸ MMP7 ▸ MMP8 ▸ MMP9 ▸
MPST ▸ MPZ ▸ MSC ▸ MST1 ▸ MST1R ▸ MT3 ▸ MT4 ▸
MTA1 ▸ MTA2 ▸ MTA3 ▸ MTOR ▸ MTX1 ▸ MUC1 ▸ MUC12 ▸
MUC13 ▸ MUC15 ▸ MUC16 ▸ MUC17 ▸ MUC19 ▸ MUC2 ▸ MUC20 ▸
MUC21 ▸ MUC22 ▸ MUC4 ▸ MUC6 ▸ MUC7 ▸ MUC8 ▸ MYC ▸
MYLIP ▸ NA ▸ NAB1 ▸ NAB2 ▸ NACA ▸ NAIP ▸ NANOG ▸
NANOS2 ▸ NDUFS1 ▸ NEO1 ▸ NFATC2 ▸ NFE2L2 ▸ NFKBIA ▸ NGF ▸
NGFR ▸ NGFRAP1 ▸ NLRC4 ▸ NLRC5 ▸ NLRP1 ▸ NLRP3 ▸ NLRP5 ▸
NLRP7 ▸ NMT2 ▸ NOD1 ▸ NOD2 ▸ NODAL ▸ NOS1 ▸ NOS2 ▸
NOS3 ▸ NOTCH1 ▸ NOX1 ▸ NOX3 ▸ NOX4 ▸ NOX5 ▸ NPM1 ▸
NPPA ▸ NPS ▸ NPY6R ▸ NR0B1 ▸ NR3C1 ▸ NTF3 ▸ NTF4 ▸
NTN1 ▸ NUAK1 ▸ NUCB2 ▸ NUMA1 ▸ NUP153 ▸ NUP210 ▸ NUP214 ▸
NUP43 ▸ NUP62 ▸ NVL ▸ ODC1 ▸ P2RX7 ▸ PAEP ▸ PAF1 ▸
PAK1 ▸ PAK2 ▸ PAN2 ▸ PAN3 ▸ PANX1 ▸ PARG ▸ PAWR ▸
PC ▸ PCBD1 ▸ PCNA ▸ PDCD1 ▸ PDCD10 ▸ PDCD11 ▸ PDCD2 ▸
PDCD4 ▸ PDCD5 ▸ PDCD6 ▸ PDCD7 ▸ PDE10A ▸ PDE5A ▸ PDGFB ▸
PDLIM7 ▸ PEA15 ▸ PGF ▸ PGP ▸ PI3 ▸ PICALM ▸ PIDD ▸
PIK3CA ▸ PIK3R1 ▸ PIN1 ▸ PIP5K1A ▸ PLA2G4A ▸ PLA2G4B ▸ PLCG1 ▸
PLD1 ▸ PLD2 ▸ PLD3 ▸ PLD4 ▸ PLD5 ▸ PLD6 ▸ PLEKHO1 ▸
PLK1 ▸ PLOD2 ▸ PMEL ▸ PML ▸ PNPLA2 ▸ POLDIP2 ▸ PPARA ▸
PPARG ▸ PPARGC1A ▸ PPP1R3A ▸ PPP2CA ▸ PPP2R1A ▸ PPP2R2B ▸ PPP3CA ▸
PPT1 ▸ PRDX2 ▸ PRF1 ▸ PRG2 ▸ PRG3 ▸ PRG4 ▸ PRKAA1 ▸
PRKAA2 ▸ PRKAB1 ▸ PRKAB2 ▸ PRKACB ▸ PRKACG ▸ PRKAG1 ▸ PRKAG2 ▸
PRKAR1A ▸ PRKAR1B ▸ PRKAR2A ▸ PRKAR2B ▸ PRKCA ▸ PRKCD ▸ PRKCG ▸
PRKDC ▸ PRNP ▸ PSEN1 ▸ PSENEN ▸ PSIP1 ▸ PSMB9 ▸ PSMD10 ▸
PTBP1 ▸ PTCH1 ▸ PTEN ▸ PTGES3 ▸ PTGS2 ▸ PTH ▸ PTHLH ▸
PTK2 ▸ PTMA ▸ PTPN11 ▸ PTX3 ▸ PTX4 ▸ PXN ▸ QRICH1 ▸
QRICH2 ▸ RABEP1 ▸ RAC1 ▸ RAC2 ▸ RAC3 ▸ RAD1 ▸ RAD17 ▸
RAD18 ▸ RAD21 ▸ RAD50 ▸ RAD51 ▸ RAD52 ▸ RAF1 ▸ RARA ▸
RASA1 ▸ RB1 ▸ RBBP4 ▸ RBBP7 ▸ RBL2 ▸ RBX1 ▸ RENBP ▸
RHO ▸ RIPK1 ▸ RIPK2 ▸ RIPK3 ▸ RIPK4 ▸ RNF19A ▸ RNF2 ▸
ROCK1 ▸ ROCK2 ▸ RRAS ▸ RUNX3 ▸ S100A12 ▸ SAA1 ▸ SARS2 ▸
SATB1 ▸ SAV1 ▸ SCAF11 ▸ SDC2 ▸ SDS ▸ SEC14L2 ▸ SEPT4 ▸
SERP2 ▸ SERPINA1 ▸ SERPINB9 ▸ SERPINF1 ▸ SETBP1 ▸ SETD2 ▸ SHC1 ▸
SHH ▸ SIVA1 ▸ SKP1 ▸ SLC17A5 ▸ SLC9A1 ▸ SLCO6A1 ▸ SLPI ▸
SMAD3 ▸ SMAD4 ▸ SMAD7 ▸ SMARCA2 ▸ SMARCA4 ▸ SMARCB1 ▸ SMARCC1 ▸
SMARCC2 ▸ SMARCD1 ▸ SMARCD2 ▸ SMARCE1 ▸ SMPD1 ▸ SMPD2 ▸ SNAP25 ▸
SOAT1 ▸ SOCS5 ▸ SOD1 ▸ SOD2 ▸ SOD3 ▸ SP1 ▸ SPP1 ▸
SREBF1 ▸ SREBF2 ▸ STAT1 ▸ STAT3 ▸ STC1 ▸ STK24 ▸ STS ▸
STSP1 ▸ STX1A ▸ STX2 ▸ SUB1 ▸ SYF2 ▸ SYK ▸ SYT1 ▸
TAC1 ▸ TAC3 ▸ TAC4 ▸ TARDBP ▸ TAT ▸ TCF12 ▸ TCF15 ▸
TCF19 ▸ TCF20 ▸ TCF21 ▸ TCF23 ▸ TCF24 ▸ TCF25 ▸ TCF3 ▸
TCF4 ▸ TCF7 ▸ TCHP ▸ TET1 ▸ TET2 ▸ TET3 ▸ TFAP2A ▸
TGFB1 ▸ TGFB3 ▸ TGM2 ▸ THAP11 ▸ THBS1 ▸ TIMP3 ▸ TLR1 ▸
TLR10 ▸ TLR2 ▸ TLR3 ▸ TLR4 ▸ TLR5 ▸ TLR6 ▸ TLR7 ▸
TLR8 ▸ TLR9 ▸ TMED7 ▸ TNFRSF10A ▸ TNFRSF10B ▸ TNFRSF1A ▸ TNFRSF1B ▸
TNFRSF25 ▸ TNFRSF8 ▸ TNFSF12 ▸ TNS4 ▸ TOP1 ▸ TP73 ▸ TRA ▸
TRAF1 ▸ TRAF2 ▸ TRAF3 ▸ TRAF4 ▸ TRAF5 ▸ TRAF6 ▸ TRAF7 ▸
TRIM28 ▸ TSC22D3 ▸ TXN ▸ TYR ▸ UBC ▸ UBE4B ▸ UCN ▸
UCP2 ▸ UNC5B ▸ UPK3B ▸ VCP ▸ VDAC1 ▸ VDAC2 ▸ VDAC3 ▸
VEGFA ▸ VIM ▸ VIMP ▸ VIP ▸ WAS ▸ WDR61 ▸ WNK1 ▸
WNK3 ▸ WNT1 ▸ WNT3A ▸ XAF1 ▸ XIAP ▸ XRCC6 ▸ YWHAE ▸
YWHAG ▸ ZBTB16 ▸ ZGLP1 ▸
Data information
Please see the Gene Interactions Track Manual.