Human Gene ZNF106 (ENST00000564754.7_12) from GENCODE V47lift37
  Description: zinc finger protein 106, transcript variant 8 (from RefSeq NM_001381994.1)
Gencode Transcript: ENST00000564754.7_12
Gencode Gene: ENSG00000103994.18_19
Transcript (Including UTRs)
   Position: hg19 chr15:42,705,021-42,783,339 Size: 78,319 Total Exon Count: 22 Strand: -
Coding Region
   Position: hg19 chr15:42,709,502-42,764,487 Size: 54,986 Coding Exon Count: 21 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr15:42,705,021-42,783,339)mRNA (may differ from genome)Protein (1906 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIPubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: H3BSS6_HUMAN
DESCRIPTION: SubName: Full=Zinc finger protein 106 homolog; Flags: Fragment;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 97.16 RPKM in Muscle - Skeletal
Total median expression: 618.53 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -85.50194-0.441 Picture PostScript Text
3' UTR -1381.004481-0.308 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like

Pfam Domains:
PF00400 - WD domain, G-beta repeat

SCOP Domains:
50952 - Soluble quinoprotein glucose dehydrogenase
50960 - TolB, C-terminal domain
63825 - YWTD domain
63829 - Calcium-dependent phosphotriesterase
69304 - Tricorn protease N-terminal domain
101898 - NHL repeat
50965 - Galactose oxidase, central domain
75011 - 3-carboxy-cis,cis-mucoante lactonizing enzyme
101908 - Putative isomerase YbhE
117289 - Nucleoporin domain
50969 - YVTN repeat-like/Quinoprotein amine dehydrogenase
50974 - Nitrous oxide reductase, N-terminal domain
50978 - WD40 repeat-like
50993 - Peptidase/esterase 'gauge' domain
69322 - Tricorn protease domain 2
50998 - Quinoprotein alcohol dehydrogenase-like
51004 - C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase
82171 - DPP6 N-terminal domain-like
57667 - beta-beta-alpha zinc fingers

ModBase Predicted Comparative 3D Structure on H3BSS6
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003676 nucleic acid binding


-  Descriptions from all associated GenBank mRNAs
  AF205632 - Homo sapiens zinc finger protein 106 (ZFP106) mRNA, complete cds.
AK226132 - Homo sapiens mRNA for zinc finger protein 106 homolog, clone: fh08818.
AL832367 - Homo sapiens mRNA; cDNA DKFZp451A177 (from clone DKFZp451A177).
AL833301 - Homo sapiens mRNA; cDNA DKFZp451K069 (from clone DKFZp451K069).
AL832455 - Homo sapiens mRNA; cDNA DKFZp451K071 (from clone DKFZp451K071).
AL832352 - Homo sapiens mRNA; cDNA DKFZp451C216 (from clone DKFZp451C216).
BX648629 - Homo sapiens mRNA; cDNA DKFZp451A239 (from clone DKFZp451A239).
AL831983 - Homo sapiens mRNA; cDNA DKFZp451F203 (from clone DKFZp451F203).
AK127741 - Homo sapiens cDNA FLJ45841 fis, clone NTONG2008483, moderately similar to Homo sapiens zinc finger protein 106 (ZFP106).
AL832014 - Homo sapiens mRNA; cDNA DKFZp451E204 (from clone DKFZp451E204).
AK302735 - Homo sapiens cDNA FLJ56182 complete cds, highly similar to Zinc finger protein 106.
BC156040 - Synthetic construct Homo sapiens clone IMAGE:100062340, MGC:190469 zinc finger protein 106 homolog (mouse) (ZFP106) mRNA, encodes complete protein.
BC172483 - Synthetic construct Homo sapiens clone IMAGE:100069177, MGC:199188 zinc finger protein 106 homolog (mouse) (ZFP106) mRNA, encodes complete protein.
AK055517 - Homo sapiens cDNA FLJ30955 fis, clone HCASM2000156.
BC014922 - Homo sapiens cDNA clone IMAGE:3908444, partial cds.
JD531310 - Sequence 512334 from Patent EP1572962.
JD511111 - Sequence 492135 from Patent EP1572962.
JD150225 - Sequence 131249 from Patent EP1572962.
JD264284 - Sequence 245308 from Patent EP1572962.
JD561668 - Sequence 542692 from Patent EP1572962.
JD507124 - Sequence 488148 from Patent EP1572962.
JD240283 - Sequence 221307 from Patent EP1572962.
JD429156 - Sequence 410180 from Patent EP1572962.
JD184419 - Sequence 165443 from Patent EP1572962.
JD233932 - Sequence 214956 from Patent EP1572962.
JD155965 - Sequence 136989 from Patent EP1572962.
JD429264 - Sequence 410288 from Patent EP1572962.
JD061505 - Sequence 42529 from Patent EP1572962.
JD506460 - Sequence 487484 from Patent EP1572962.
JD286272 - Sequence 267296 from Patent EP1572962.
JD356875 - Sequence 337899 from Patent EP1572962.
JD250348 - Sequence 231372 from Patent EP1572962.
JD325628 - Sequence 306652 from Patent EP1572962.
JD503114 - Sequence 484138 from Patent EP1572962.
JD197501 - Sequence 178525 from Patent EP1572962.
JD147067 - Sequence 128091 from Patent EP1572962.
JD050882 - Sequence 31906 from Patent EP1572962.
DQ591620 - Homo sapiens piRNA piR-58732, complete sequence.
JD537499 - Sequence 518523 from Patent EP1572962.
JD399827 - Sequence 380851 from Patent EP1572962.
JD422954 - Sequence 403978 from Patent EP1572962.
JD468312 - Sequence 449336 from Patent EP1572962.
JD219343 - Sequence 200367 from Patent EP1572962.
JD307559 - Sequence 288583 from Patent EP1572962.
JD436930 - Sequence 417954 from Patent EP1572962.
JD273359 - Sequence 254383 from Patent EP1572962.
JD267969 - Sequence 248993 from Patent EP1572962.
JD240599 - Sequence 221623 from Patent EP1572962.
JD083907 - Sequence 64931 from Patent EP1572962.
JD447607 - Sequence 428631 from Patent EP1572962.
JD331975 - Sequence 312999 from Patent EP1572962.
JD308818 - Sequence 289842 from Patent EP1572962.
JD096360 - Sequence 77384 from Patent EP1572962.
JD334173 - Sequence 315197 from Patent EP1572962.
JD177458 - Sequence 158482 from Patent EP1572962.
JD055821 - Sequence 36845 from Patent EP1572962.
JD306547 - Sequence 287571 from Patent EP1572962.
JD169887 - Sequence 150911 from Patent EP1572962.
JD529548 - Sequence 510572 from Patent EP1572962.
JD557487 - Sequence 538511 from Patent EP1572962.
JD400655 - Sequence 381679 from Patent EP1572962.
JD393104 - Sequence 374128 from Patent EP1572962.
JD084415 - Sequence 65439 from Patent EP1572962.
JD169886 - Sequence 150910 from Patent EP1572962.
JD045866 - Sequence 26890 from Patent EP1572962.
JD138935 - Sequence 119959 from Patent EP1572962.
JD076592 - Sequence 57616 from Patent EP1572962.
JD097677 - Sequence 78701 from Patent EP1572962.
JD512754 - Sequence 493778 from Patent EP1572962.
JD412786 - Sequence 393810 from Patent EP1572962.
JD197806 - Sequence 178830 from Patent EP1572962.
JD212415 - Sequence 193439 from Patent EP1572962.
JD135914 - Sequence 116938 from Patent EP1572962.
JD194719 - Sequence 175743 from Patent EP1572962.
JD135509 - Sequence 116533 from Patent EP1572962.
JD395694 - Sequence 376718 from Patent EP1572962.
JD472013 - Sequence 453037 from Patent EP1572962.
AK024726 - Homo sapiens cDNA: FLJ21073 fis, clone CAS02025.
JD055159 - Sequence 36183 from Patent EP1572962.
JD340941 - Sequence 321965 from Patent EP1572962.
JD180111 - Sequence 161135 from Patent EP1572962.
JD421718 - Sequence 402742 from Patent EP1572962.
JD521185 - Sequence 502209 from Patent EP1572962.
JD189722 - Sequence 170746 from Patent EP1572962.
JD441887 - Sequence 422911 from Patent EP1572962.
JD203364 - Sequence 184388 from Patent EP1572962.
JD498767 - Sequence 479791 from Patent EP1572962.
JD353261 - Sequence 334285 from Patent EP1572962.
JD166359 - Sequence 147383 from Patent EP1572962.
JD316707 - Sequence 297731 from Patent EP1572962.
JD265132 - Sequence 246156 from Patent EP1572962.
JD184603 - Sequence 165627 from Patent EP1572962.
JD549080 - Sequence 530104 from Patent EP1572962.
JD565115 - Sequence 546139 from Patent EP1572962.
AK091929 - Homo sapiens cDNA FLJ34610 fis, clone KIDNE2014087, moderately similar to Zinc finger protein 106.
AX747260 - Sequence 785 from Patent EP1308459.
AK057410 - Homo sapiens cDNA FLJ32848 fis, clone TESTI2003413, moderately similar to Zinc finger protein 106.
AK294529 - Homo sapiens cDNA FLJ60081 partial cds, highly similar to Zinc finger protein 106.
BC111396 - Homo sapiens zinc finger protein 106 homolog (mouse), mRNA (cDNA clone IMAGE:4250488), partial cds.
BC058023 - Homo sapiens zinc finger protein 106 homolog (mouse), mRNA (cDNA clone IMAGE:4271126), partial cds.
BC070244 - Homo sapiens zinc finger protein 106 homolog (mouse), mRNA (cDNA clone IMAGE:4244669), partial cds.
BX649141 - Homo sapiens mRNA; cDNA DKFZp686N20157 (from clone DKFZp686N20157).
BC029366 - Homo sapiens zinc finger protein 106 homolog (mouse), mRNA (cDNA clone IMAGE:4289710), partial cds.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000564754.1, ENST00000564754.2, ENST00000564754.3, ENST00000564754.4, ENST00000564754.5, ENST00000564754.6, H3BSS6, H3BSS6_HUMAN, NM_001381994, uc325tor.1, uc325tor.2, ZNF106
UCSC ID: ENST00000564754.7_12
RefSeq Accession: NM_001366845.3
Protein: H3BSS6

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.