The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9Y2K1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0003676 nucleic acid binding GO:0003677 DNA binding GO:0005515 protein binding GO:0042803 protein homodimerization activity GO:0046872 metal ion binding GO:0046982 protein heterodimerization activity GO:0070530 K63-linked polyubiquitin binding
Biological Process: GO:0000122 negative regulation of transcription from RNA polymerase II promoter GO:0002376 immune system process GO:0002711 positive regulation of T cell mediated immunity GO:0006281 DNA repair GO:0006338 chromatin remodeling GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006974 cellular response to DNA damage stimulus GO:0019985 translesion synthesis GO:0030154 cell differentiation GO:0030183 B cell differentiation GO:0032825 positive regulation of natural killer cell differentiation GO:0033077 T cell differentiation in thymus GO:0034644 cellular response to UV GO:0042789 mRNA transcription from RNA polymerase II promoter GO:0045087 innate immune response GO:0045582 positive regulation of T cell differentiation GO:0048538 thymus development GO:0051260 protein homooligomerization GO:2000176 positive regulation of pro-T cell differentiation
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
