ID:SRPRB_HUMAN DESCRIPTION: RecName: Full=Signal recognition particle receptor subunit beta; Short=SR-beta; AltName: Full=Protein APMCF1; FUNCTION: Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR (By similarity). SUBUNIT: Heterodimer with SRPR (By similarity). SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity). SIMILARITY: Belongs to the SRP receptor beta subunit family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00025 - ADP-ribosylation factor family PF01926 - 50S ribosome-binding GTPase PF02421 - Ferrous iron transport protein B PF09439 - Signal recognition particle receptor beta subunit
ModBase Predicted Comparative 3D Structure on Q9Y5M8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
