Human Gene RANBP1 (ENST00000430524.6_8) from GENCODE V47lift37
  Description: RAN binding protein 1, transcript variant 1 (from RefSeq NM_001278639.2)
Gencode Transcript: ENST00000430524.6_8
Gencode Gene: ENSG00000099901.18_17
Transcript (Including UTRs)
   Position: hg19 chr22:20,103,627-20,114,878 Size: 11,252 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr22:20,103,708-20,114,575 Size: 10,868 Coding Exon Count: 6 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsPathwaysOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr22:20,103,627-20,114,878)mRNA (may differ from genome)Protein (278 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 49.60 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 796.30 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -24.4081-0.301 Picture PostScript Text
3' UTR -40.00303-0.132 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologGenome Browser
Gene DetailsGene Details   Gene Details
Gene SorterGene Sorter   Gene Sorter
 RGD   SGD
     Protein Sequence
     Alignment

-  Descriptions from all associated GenBank mRNAs
  AK097659 - Homo sapiens cDNA FLJ40340 fis, clone TESTI2032681, moderately similar to RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN.
D38076 - Homo sapiens RanBP1 mRNA for Ran-binding protein 1, complete cds.
HM005634 - Homo sapiens clone HTL-S-221n testis secretory sperm-binding protein Li 221n mRNA, complete cds.
AK300927 - Homo sapiens cDNA FLJ54173 complete cds, highly similar to Ran-specific GTPase-activating protein.
AK223506 - Homo sapiens mRNA for RAN binding protein 1 variant, clone: FCC121F08.
X83617 - H.sapiens mRNA for RanBP1.
AK293502 - Homo sapiens cDNA FLJ57507 complete cds, highly similar to Ran-specific GTPase-activating protein.
BC071998 - Homo sapiens RAN binding protein 1, mRNA (cDNA clone IMAGE:3935906), containing frame-shift errors.
BC071999 - Homo sapiens cDNA clone IMAGE:4646958, **** WARNING: chimeric clone ****.
CR456556 - Homo sapiens RANBP1 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.RANBP1.V3).
BC152785 - Synthetic construct Homo sapiens clone IMAGE:100015946, MGC:184182 RAN binding protein 1 (RANBP1) mRNA, encodes complete protein.
AB587487 - Synthetic construct DNA, clone: pF1KB8652, Homo sapiens RANBP1 gene for RAN binding protein 1, without stop codon, in Flexi system.
CU013444 - Homo sapiens RANBP1, mRNA (cDNA clone IMAGE:100000413), complete cds, without stop codon, in Gateway system.
CU013156 - Homo sapiens RANBP1, mRNA (cDNA clone IMAGE:100000509), complete cds, with stop codon, in Gateway system.
AK094410 - Homo sapiens cDNA FLJ37091 fis, clone BRACE2017720, moderately similar to RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN.
DL491960 - Novel nucleic acids.

-  Biochemical and Signaling Pathways
  BioCarta from NCI Cancer Genome Anatomy Project
h_ranPathway - Cycling of Ran in nucleocytoplasmic transport
h_ranMSpathway - Role of Ran in mitotic spindle regulation

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000430524.1, ENST00000430524.2, ENST00000430524.3, ENST00000430524.4, ENST00000430524.5, F6WQW2, F6WQW2_HUMAN, NM_001278639, RANBP1 , uc319zir.1, uc319zir.2
UCSC ID: ENST00000430524.6_8
RefSeq Accession: NM_001278639.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.