ID:RAB38_HUMAN DESCRIPTION: RecName: Full=Ras-related protein Rab-38; AltName: Full=Melanoma antigen NY-MEL-1; FUNCTION: May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Melanosome. TISSUE SPECIFICITY: Expressed in melanocytes. PTM: Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated. SIMILARITY: Belongs to the small GTPase superfamily. Rab family. WEB RESOURCE: Name=SeattleSNPs; URL="http://pga.gs.washington.edu/data/rab38/";
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF00025 - ADP-ribosylation factor family PF00071 - Ras family PF04670 - Gtr1/RagA G protein conserved region PF08477 - Ras of Complex, Roc, domain of DAPkinase
ModBase Predicted Comparative 3D Structure on P57729
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006996 organelle organization GO:0007005 mitochondrion organization GO:0007264 small GTPase mediated signal transduction GO:0015031 protein transport GO:0016192 vesicle-mediated transport GO:0035646 endosome to melanosome transport GO:0043687 post-translational protein modification GO:0060155 platelet dense granule organization GO:0072657 protein localization to membrane GO:0090383 phagosome acidification GO:1903232 melanosome assembly
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
