Human Gene PPP2R5C (ENST00000694906.1_4) from GENCODE V47lift37
  Description: protein phosphatase 2 regulatory subunit B'gamma, transcript variant 8 (from RefSeq NM_001352913.2)
Gencode Transcript: ENST00000694906.1_4
Gencode Gene: ENSG00000078304.20_18
Transcript (Including UTRs)
   Position: hg19 chr14:102,228,046-102,394,314 Size: 166,269 Total Exon Count: 16 Strand: +
Coding Region
   Position: hg19 chr14:102,228,231-102,391,609 Size: 163,379 Coding Exon Count: 16 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr14:102,228,046-102,394,314)mRNA (may differ from genome)Protein (579 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: PPP2R5C
Diseases sorted by gene-association score: ectrodactyly, ectodermal dysplasia, and cleft lip/palate syndrome 3 (12), eec syndrome (7)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -115.80185-0.626 Picture PostScript Text
3' UTR -732.102705-0.271 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologGenome Browser
Gene DetailsGene Details   Gene Details
Gene SorterGene Sorter   Gene Sorter
 RGDEnsembl  SGD
     Protein Sequence
     Alignment

-  Descriptions from all associated GenBank mRNAs
  LF384889 - JP 2014500723-A/192392: Polycomb-Associated Non-Coding RNAs.
AL834350 - Homo sapiens mRNA; cDNA DKFZp761H0317 (from clone DKFZp761H0317).
BC051442 - Homo sapiens cDNA clone IMAGE:6163196, partial cds.
AK131391 - Homo sapiens cDNA FLJ16473 fis, clone BRHIP3026052, highly similar to Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, gamma isoform.
AK302470 - Homo sapiens cDNA FLJ57234 complete cds, highly similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform.
AK315072 - Homo sapiens cDNA, FLJ96026.
Z69030 - H.sapiens mRNA for gamma 1 isoform of 61kDa regulatory subunit of PP2A.
U37352 - Human protein phosphatase 2A B'alpha1 regulatory subunit mRNA, complete cds.
BC016183 - Homo sapiens protein phosphatase 2, regulatory subunit B', gamma isoform, mRNA (cDNA clone MGC:23064 IMAGE:4855950), complete cds.
KJ901658 - Synthetic construct Homo sapiens clone ccsbBroadEn_11052 PPP2R5C gene, encodes complete protein.
AB451341 - Homo sapiens PPP2R5C mRNA for serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, partial cds, clone: FLJ03003AAAF.
D26445 - Homo sapiens KIAA0044 mRNA, partial cds.
L42375 - Homo sapiens protein phosphatase 2A B56-gamma1 (PP2A) mRNA, 3' end of cds.
AB463199 - Synthetic construct DNA, clone: pF1KA0044, Homo sapiens PPP2R5C gene for protein phosphatase 2, regulatory subunit B', gamma isoform, without stop codon, in Flexi system.
BX248254 - human full-length cDNA clone CS0DF017YJ08 of Fetal brain of Homo sapiens (human).
MA620466 - JP 2018138019-A/192392: Polycomb-Associated Non-Coding RNAs.
AK295449 - Homo sapiens cDNA FLJ57986 complete cds, highly similar to Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform.
CU677587 - Synthetic construct Homo sapiens gateway clone IMAGE:100017630 5' read PPP2R5C mRNA.
LF209657 - JP 2014500723-A/17160: Polycomb-Associated Non-Coding RNAs.
LF330591 - JP 2014500723-A/138094: Polycomb-Associated Non-Coding RNAs.
JD083654 - Sequence 64678 from Patent EP1572962.
JD555303 - Sequence 536327 from Patent EP1572962.
JD232600 - Sequence 213624 from Patent EP1572962.
JD142913 - Sequence 123937 from Patent EP1572962.
JD207003 - Sequence 188027 from Patent EP1572962.
JD263036 - Sequence 244060 from Patent EP1572962.
JD219767 - Sequence 200791 from Patent EP1572962.
JD224682 - Sequence 205706 from Patent EP1572962.
JD149641 - Sequence 130665 from Patent EP1572962.
JD160423 - Sequence 141447 from Patent EP1572962.
JD092420 - Sequence 73444 from Patent EP1572962.
JD563869 - Sequence 544893 from Patent EP1572962.
JD458772 - Sequence 439796 from Patent EP1572962.
JD537562 - Sequence 518586 from Patent EP1572962.
JD375861 - Sequence 356885 from Patent EP1572962.
JD432153 - Sequence 413177 from Patent EP1572962.
JD171300 - Sequence 152324 from Patent EP1572962.
JD488203 - Sequence 469227 from Patent EP1572962.
JD423691 - Sequence 404715 from Patent EP1572962.
JD371686 - Sequence 352710 from Patent EP1572962.
JD398866 - Sequence 379890 from Patent EP1572962.
JD204263 - Sequence 185287 from Patent EP1572962.
JD302504 - Sequence 283528 from Patent EP1572962.
JD346840 - Sequence 327864 from Patent EP1572962.
JD296278 - Sequence 277302 from Patent EP1572962.
JD420715 - Sequence 401739 from Patent EP1572962.
JD333671 - Sequence 314695 from Patent EP1572962.
JD274274 - Sequence 255298 from Patent EP1572962.
JD436187 - Sequence 417211 from Patent EP1572962.
JD109358 - Sequence 90382 from Patent EP1572962.
JD091716 - Sequence 72740 from Patent EP1572962.
JD126567 - Sequence 107591 from Patent EP1572962.
JD345317 - Sequence 326341 from Patent EP1572962.
JD224345 - Sequence 205369 from Patent EP1572962.
MA566168 - JP 2018138019-A/138094: Polycomb-Associated Non-Coding RNAs.
MA445234 - JP 2018138019-A/17160: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A8Q3WKR3, A0A8Q3WKR3_HUMAN, NM_001352913, PPP2R5C , uc330zay.1, uc330zay.2
UCSC ID: ENST00000694906.1_4
RefSeq Accession: NM_001352913.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.