The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8N5Y8
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0003950 NAD+ ADP-ribosyltransferase activity GO:0005515 protein binding GO:0016740 transferase activity GO:0016757 transferase activity, transferring glycosyl groups GO:0019900 kinase binding GO:0043539 protein serine/threonine kinase activator activity
Biological Process: GO:0006471 protein ADP-ribosylation GO:0006986 response to unfolded protein GO:0006987 activation of signaling protein activity involved in unfolded protein response GO:0030968 endoplasmic reticulum unfolded protein response GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway GO:0060548 negative regulation of cell death GO:0070213 protein auto-ADP-ribosylation GO:0071902 positive regulation of protein serine/threonine kinase activity GO:1990830 cellular response to leukemia inhibitory factor
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
