The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P55055
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0003677 DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding GO:0003707 steroid hormone receptor activity GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0005515 protein binding GO:0008270 zinc ion binding GO:0034191 apolipoprotein A-I receptor binding GO:0043565 sequence-specific DNA binding GO:0046872 metal ion binding GO:0046965 retinoid X receptor binding GO:0051117 ATPase binding
Biological Process: GO:0000122 negative regulation of transcription from RNA polymerase II promoter GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0006367 transcription initiation from RNA polymerase II promoter GO:0010628 positive regulation of gene expression GO:0010629 negative regulation of gene expression GO:0010745 negative regulation of macrophage derived foam cell differentiation GO:0010867 positive regulation of triglyceride biosynthetic process GO:0010875 positive regulation of cholesterol efflux GO:0010884 positive regulation of lipid storage GO:0010887 negative regulation of cholesterol storage GO:0032270 positive regulation of cellular protein metabolic process GO:0032369 negative regulation of lipid transport GO:0032376 positive regulation of cholesterol transport GO:0042632 cholesterol homeostasis GO:0043401 steroid hormone mediated signaling pathway GO:0044255 cellular lipid metabolic process GO:0045723 positive regulation of fatty acid biosynthetic process GO:0045861 negative regulation of proteolysis GO:0045892 negative regulation of transcription, DNA-templated GO:0045893 positive regulation of transcription, DNA-templated GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0048384 retinoic acid receptor signaling pathway GO:0048550 negative regulation of pinocytosis GO:0051006 positive regulation of lipoprotein lipase activity GO:0055088 lipid homeostasis GO:0060336 negative regulation of interferon-gamma-mediated signaling pathway GO:0090108 positive regulation of high-density lipoprotein particle assembly GO:0090187 positive regulation of pancreatic juice secretion GO:0090340 positive regulation of secretion of lysosomal enzymes
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
