The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9Y2X3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
KJ893947 - Synthetic construct Homo sapiens clone ccsbBroadEn_03341 NOP58 gene, encodes complete protein. AL117554 - Homo sapiens mRNA; cDNA DKFZp564H2171 (from clone DKFZp564H2171). AK307396 - Homo sapiens cDNA, FLJ97344. BC001707 - Homo sapiens, Similar to nucleolar protein NOP5/NOP58, clone IMAGE:3542130, mRNA. BC018805 - Homo sapiens NOP58 ribonucleoprotein homolog (yeast), mRNA (cDNA clone IMAGE:4905882). BC009306 - Homo sapiens NOP58 ribonucleoprotein homolog (yeast), mRNA (cDNA clone IMAGE:4301008), partial cds. BC032592 - Homo sapiens NOP58 ribonucleoprotein homolog (yeast), mRNA (cDNA clone MGC:45092 IMAGE:5527148), complete cds. EU176490 - Synthetic construct Homo sapiens clone IMAGE:100011348; FLH166645.01L; RZPDo839E03253D nucleolar protein NOP5/NOP58 (NOP5/NOP58) gene, encodes complete protein. DQ890868 - Synthetic construct clone IMAGE:100003498; FLH166646.01X; RZPDo839B0988D nucleolar protein NOP5/NOP58 (NOP5/NOP58) gene, encodes complete protein. AB528451 - Synthetic construct DNA, clone: pF1KB0487, Homo sapiens NOP5 gene for NOP58 ribonucleoprotein homolog, without stop codon, in Flexi system. AF123534 - Homo sapiens nucleolar protein NOP5/NOP58 mRNA, complete cds. AF263608 - Homo sapiens nucleolar protein 5 (NOP5) mRNA, complete cds. AK023975 - Homo sapiens cDNA FLJ13913 fis, clone Y79AA1000231, highly similar to Nucleolar protein NOP5. AF161469 - Homo sapiens HSPC120 mRNA, complete cds. AK300844 - Homo sapiens cDNA FLJ56668 complete cds, highly similar to Nucleolar protein NOP5. JD529960 - Sequence 510984 from Patent EP1572962. CU689436 - Synthetic construct Homo sapiens gateway clone IMAGE:100019789 5' read NOP5/NOP58 mRNA. DQ586402 - Homo sapiens piRNA piR-53514, complete sequence. JD110211 - Sequence 91235 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q9Y2X3 (Reactome details) participates in the following event(s):
R-HSA-4570489 SUMOylation of NOP58 with SUMO2 R-HSA-4570467 SUMOylation of NOP58 with SUMO1 R-HSA-6790907 Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides R-HSA-6790906 EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 R-HSA-4570464 SUMOylation of RNA binding proteins R-HSA-3108232 SUMO E3 ligases SUMOylate target proteins R-HSA-2990846 SUMOylation R-HSA-6790901 rRNA modification in the nucleus and cytosol R-HSA-597592 Post-translational protein modification R-HSA-8868773 rRNA processing in the nucleus and cytosol R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-392499 Metabolism of proteins R-HSA-72312 rRNA processing R-HSA-8953854 Metabolism of RNA
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
