The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9BT40
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0001701 in utero embryonic development GO:0001933 negative regulation of protein phosphorylation GO:0005979 regulation of glycogen biosynthetic process GO:0006469 negative regulation of protein kinase activity GO:0006661 phosphatidylinositol biosynthetic process GO:0007186 G-protein coupled receptor signaling pathway GO:0010801 negative regulation of peptidyl-threonine phosphorylation GO:0010829 negative regulation of glucose transport GO:0016311 dephosphorylation GO:0030036 actin cytoskeleton organization GO:0032868 response to insulin GO:0032869 cellular response to insulin stimulus GO:0032870 cellular response to hormone stimulus GO:0033137 negative regulation of peptidyl-serine phosphorylation GO:0035305 negative regulation of dephosphorylation GO:0035810 positive regulation of urine volume GO:0042593 glucose homeostasis GO:0043407 negative regulation of MAP kinase activity GO:0043922 negative regulation by host of viral transcription GO:0045719 negative regulation of glycogen biosynthetic process GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate GO:0045892 negative regulation of transcription, DNA-templated GO:0045893 positive regulation of transcription, DNA-templated GO:0046627 negative regulation of insulin receptor signaling pathway GO:0046855 inositol phosphate dephosphorylation GO:0046856 phosphatidylinositol dephosphorylation GO:0051497 negative regulation of stress fiber assembly GO:0051898 negative regulation of protein kinase B signaling GO:0051926 negative regulation of calcium ion transport GO:0071320 cellular response to cAMP GO:0071356 cellular response to tumor necrosis factor GO:0071364 cellular response to epidermal growth factor stimulus GO:0072659 protein localization to plasma membrane GO:0090315 negative regulation of protein targeting to membrane GO:0097178 ruffle assembly GO:2000466 negative regulation of glycogen (starch) synthase activity GO:2001153 positive regulation of renal water transport
Protein Q9BT40 (Reactome details) participates in the following event(s):
R-HSA-1675949 PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane R-HSA-1676177 PI(4,5)P2 is dephosphorylated to PI4P by SYNJ/INPP5[1] at the plasma membrane R-HSA-1660499 Synthesis of PIPs at the plasma membrane R-HSA-1483255 PI Metabolism R-HSA-1483257 Phospholipid metabolism R-HSA-556833 Metabolism of lipids R-HSA-1430728 Metabolism