Human Gene GPR137 (ENST00000313074.7_1) from GENCODE V47lift37
  Description: G protein-coupled receptor 137, transcript variant 3 (from RefSeq NM_020155.4)
Gencode Transcript: ENST00000313074.7_1
Gencode Gene: ENSG00000173264.16_17
Transcript (Including UTRs)
   Position: hg19 chr11:64,053,892-64,056,963 Size: 3,072 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg19 chr11:64,053,997-64,056,837 Size: 2,841 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:64,053,892-64,056,963)mRNA (may differ from genome)Protein (417 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: G137A_HUMAN
DESCRIPTION: RecName: Full=Integral membrane protein GPR137; AltName: Full=Transmembrane 7 superfamily member 1-like 1 protein;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).
SIMILARITY: Belongs to the GPR137 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 117.24 RPKM in Testis
Total median expression: 697.18 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -23.90105-0.228 Picture PostScript Text
3' UTR -41.20126-0.327 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q96N19
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
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-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  BC029297 - Homo sapiens G protein-coupled receptor 137, mRNA (cDNA clone IMAGE:5174640).
AK300209 - Homo sapiens cDNA FLJ59754 complete cds, highly similar to Mus musculus G protein-coupled receptor 137 (Gpr137), mRNA.
LF211207 - JP 2014500723-A/18710: Polycomb-Associated Non-Coding RNAs.
AK302256 - Homo sapiens cDNA FLJ58705 complete cds, highly similar to Mus musculus G protein-coupled receptor 137 (Gpr137), mRNA.
BC020396 - Homo sapiens G protein-coupled receptor 137, mRNA (cDNA clone IMAGE:4181989).
BC035002 - Homo sapiens G protein-coupled receptor 137, mRNA (cDNA clone MGC:33256 IMAGE:5265415), complete cds.
AK056094 - Homo sapiens cDNA FLJ31532 fis, clone NT2RI2000597.
AJ250392 - Homo sapiens mRNA for chromosome 11 hypothetical protein (ORF4).
BC033920 - Homo sapiens G protein-coupled receptor 137, mRNA (cDNA clone MGC:31834 IMAGE:5019895), complete cds.
JD408274 - Sequence 389298 from Patent EP1572962.
JD264065 - Sequence 245089 from Patent EP1572962.
LF344606 - JP 2014500723-A/152109: Polycomb-Associated Non-Coding RNAs.
JD377418 - Sequence 358442 from Patent EP1572962.
JD282181 - Sequence 263205 from Patent EP1572962.
MA580183 - JP 2018138019-A/152109: Polycomb-Associated Non-Coding RNAs.
MA446784 - JP 2018138019-A/18710: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B4DTG7, B7Z7M1, C11orf4, ENST00000313074.1, ENST00000313074.2, ENST00000313074.3, ENST00000313074.4, ENST00000313074.5, ENST00000313074.6, G137A_HUMAN, GPR137A, NM_020155, Q4G0Y9, Q8N4K6, Q96N19, TM7SF1L1, uc317pim.1
UCSC ID: ENST00000313074.7_1
RefSeq Accession: NM_020155.4
Protein: Q96N19 (aka G137A_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.