The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P15407
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0003677 DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding GO:0005515 protein binding
Biological Process: GO:0001701 in utero embryonic development GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0006366 transcription from RNA polymerase II promoter GO:0006935 chemotaxis GO:0006968 cellular defense response GO:0007296 vitellogenesis GO:0007565 female pregnancy GO:0007612 learning GO:0008284 positive regulation of cell proliferation GO:0008285 negative regulation of cell proliferation GO:0009612 response to mechanical stimulus GO:0009615 response to virus GO:0009629 response to gravity GO:0014070 response to organic cyclic compound GO:0031668 cellular response to extracellular stimulus GO:0032570 response to progesterone GO:0034097 response to cytokine GO:0042493 response to drug GO:0042542 response to hydrogen peroxide GO:0043065 positive regulation of apoptotic process GO:0045787 positive regulation of cell cycle GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051412 response to corticosterone GO:0051591 response to cAMP GO:0060674 placenta blood vessel development GO:0061614 pri-miRNA transcription from RNA polymerase II promoter GO:2000144 positive regulation of DNA-templated transcription, initiation
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
