Human Gene FER (ENST00000281092.9_4) from GENCODE V47lift37
  Description: FER tyrosine kinase, transcript variant 5 (from RefSeq NR_146155.2)
Gencode Transcript: ENST00000281092.9_4
Gencode Gene: ENSG00000151422.14_9
Transcript (Including UTRs)
   Position: hg19 chr5:108,083,598-108,532,542 Size: 448,945 Total Exon Count: 20 Strand: +
Coding Region
   Position: hg19 chr5:108,133,884-108,523,276 Size: 389,393 Coding Exon Count: 18 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr5:108,083,598-108,532,542)mRNA (may differ from genome)Protein (822 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: FER
Diseases sorted by gene-association score: leukemia, acute myeloid (1)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 4.83 RPKM in Nerve - Tibial
Total median expression: 101.85 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -80.00309-0.259 Picture PostScript Text
3' UTR -2344.709266-0.253 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details Gene Details  
Gene SorterGene Sorter Gene Sorter  
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  AK293376 - Homo sapiens cDNA FLJ56544 complete cds, highly similar to Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2).
J03358 - Human tyrosine kinase (FER) mRNA, complete cds.
LF385214 - JP 2014500723-A/192717: Polycomb-Associated Non-Coding RNAs.
AK296874 - Homo sapiens cDNA FLJ57122 complete cds, highly similar to Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2).
AK299855 - Homo sapiens cDNA FLJ61378 complete cds, highly similar to Proto-oncogene tyrosine-protein kinase FER (EC 2.7.10.2).
BC058030 - Homo sapiens fer (fps/fes related) tyrosine kinase, mRNA (cDNA clone IMAGE:4738532), complete cds.
BC017060 - Homo sapiens fer (fps/fes related) tyrosine kinase, mRNA (cDNA clone IMAGE:3886018), partial cds.
AB636592 - Homo sapiens Pe1Fe3 mRNA for fer (fps/fes related) tyrosine kinase, complete cds.
AK315234 - Homo sapiens cDNA, FLJ96234, highly similar to Homo sapiens fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94) (FER), mRNA.
AB590037 - Synthetic construct DNA, clone: pFN21AB7308, Homo sapiens FER gene for fer (fps/fes related) tyrosine kinase, without stop codon, in Flexi system.
BC141559 - Synthetic construct Homo sapiens clone IMAGE:100014538, MGC:175304 fer (fps/fes related) tyrosine kinase (FER) mRNA, encodes complete protein.
AB636593 - Homo sapiens Pe1Fe6 mRNA for truncated fer (fps/fes related) tyrosine kinase, complete cds.
AB636594 - Homo sapiens Pe1Fe10 mRNA for truncated fer (fps/fes related) tyrosine kinase, complete cds.
JQ412173 - Homo sapiens cell-line HCT116 FerT (ferT) mRNA, complete cds.
AB636595 - Homo sapiens Pe1Fe13 mRNA for truncated fer (fps/fes related) tyrosine kinase, complete cds.
AK123847 - Homo sapiens cDNA FLJ41853 fis, clone NT2RI3004161.
MA620791 - JP 2018138019-A/192717: Polycomb-Associated Non-Coding RNAs.
JD363996 - Sequence 345020 from Patent EP1572962.
JD247506 - Sequence 228530 from Patent EP1572962.
JD197199 - Sequence 178223 from Patent EP1572962.
JD452458 - Sequence 433482 from Patent EP1572962.
JD262996 - Sequence 244020 from Patent EP1572962.
JD536252 - Sequence 517276 from Patent EP1572962.
LF341813 - JP 2014500723-A/149316: Polycomb-Associated Non-Coding RNAs.
MA577390 - JP 2018138019-A/149316: Polycomb-Associated Non-Coding RNAs.
LF341814 - JP 2014500723-A/149317: Polycomb-Associated Non-Coding RNAs.
LF341815 - JP 2014500723-A/149318: Polycomb-Associated Non-Coding RNAs.
MA577391 - JP 2018138019-A/149317: Polycomb-Associated Non-Coding RNAs.
MA577392 - JP 2018138019-A/149318: Polycomb-Associated Non-Coding RNAs.
JD037310 - Sequence 18334 from Patent EP1572962.
AK092320 - Homo sapiens cDNA FLJ35001 fis, clone OCBBF2011887.
JD023005 - Sequence 4029 from Patent EP1572962.
JD030075 - Sequence 11099 from Patent EP1572962.
JD029768 - Sequence 10792 from Patent EP1572962.
AK021888 - Homo sapiens cDNA FLJ11826 fis, clone HEMBA1006497.
LF210900 - JP 2014500723-A/18403: Polycomb-Associated Non-Coding RNAs.
LF341817 - JP 2014500723-A/149320: Polycomb-Associated Non-Coding RNAs.
MA577394 - JP 2018138019-A/149320: Polycomb-Associated Non-Coding RNAs.
MA446477 - JP 2018138019-A/18403: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000281092.1, ENST00000281092.2, ENST00000281092.3, ENST00000281092.4, ENST00000281092.5, ENST00000281092.6, ENST00000281092.7, ENST00000281092.8, NR_146155, Pe1Fe3 , uc317jvo.1, uc317jvo.2, W0S0X4, W0S0X4_HUMAN
UCSC ID: ENST00000281092.9_4
RefSeq Accession: NM_005246.4

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.