The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK295195 - Homo sapiens cDNA FLJ59518 complete cds, highly similar to Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1). FW403753 - NUCLEIC ACID COMPOUNDS FOR INHIBITING ERBB FAMILY GENE EXPRESSION AND USES THEREOFF. AB587321 - Synthetic construct DNA, clone: pF1KB3024, Homo sapiens ERBB2 gene for v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog, without stop codon, in Flexi system. AK300321 - Homo sapiens cDNA FLJ59426 complete cds, highly similar to Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1). FW403752 - NUCLEIC ACID COMPOUNDS FOR INHIBITING ERBB FAMILY GENE EXPRESSION AND USES THEREOFF. AK313683 - Homo sapiens cDNA, FLJ94272. LF213774 - JP 2014500723-A/21277: Polycomb-Associated Non-Coding RNAs. BC080193 - Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), mRNA (cDNA clone IMAGE:6178526). X03363 - Human c-erb-B-2 mRNA. M11730 - Human tyrosine kinase-type receptor (HER2) mRNA, complete cds. BC156755 - Synthetic construct Homo sapiens clone IMAGE:100062227, MGC:190211 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2) mRNA, encodes complete protein. BC167147 - Homo sapiens v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), mRNA (cDNA clone MGC:166940 IMAGE:100013444), complete cds. KJ534831 - Homo sapiens clone ERBB2_iso-A_adult-A05 v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2 isoform A (ERBB2) mRNA, partial cds, alternatively spliced. KJ534832 - Homo sapiens clone ERBB2_iso-C_fetal-F08 v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2 isoform C (ERBB2) mRNA, partial cds, alternatively spliced. KJ534964 - Homo sapiens clone ERBB2_iso-B_fetal-F09 v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2 isoform B (ERBB2) mRNA, partial cds, alternatively spliced. AK131568 - Homo sapiens cDNA FLJ16821 fis, clone TRACH3021066. MA449351 - JP 2018138019-A/21277: Polycomb-Associated Non-Coding RNAs. AK309029 - Homo sapiens cDNA, FLJ99070. BC110392 - Homo sapiens cDNA clone IMAGE:5195657. CQ894022 - Sequence 22 from Patent WO2004087207. CQ894024 - Sequence 24 from Patent WO2004087207. CQ894026 - Sequence 26 from Patent WO2004087207. CQ894028 - Sequence 28 from Patent WO2004087207. JD442760 - Sequence 423784 from Patent EP1572962. JD335030 - Sequence 316054 from Patent EP1572962. JD456181 - Sequence 437205 from Patent EP1572962. CQ894030 - Sequence 30 from Patent WO2004087207. AF177761 - Homo sapiens herstatin (HER-2) mRNA, alternatively spliced, complete cds. AK296908 - Homo sapiens cDNA FLJ55711 complete cds, highly similar to Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1). BD404060 - WO 2003091433-A/31: Expression system for stem-loop shaped RNA molecules conferring RNAi. DD115626 - Expression system for stem-loop shaped RNA molecules conferring RNAi. BD404061 - WO 2003091433-A/32: Expression system for stem-loop shaped RNA molecules conferring RNAi. DD115627 - Expression system for stem-loop shaped RNA molecules conferring RNAi. BD404062 - WO 2003091433-A/33: Expression system for stem-loop shaped RNA molecules conferring RNAi. DD115628 - Expression system for stem-loop shaped RNA molecules conferring RNAi. BD404063 - WO 2003091433-A/34: Expression system for stem-loop shaped RNA molecules conferring RNAi. DD115629 - Expression system for stem-loop shaped RNA molecules conferring RNAi. HM437238 - Homo sapiens receptor tyrosine-protein kinase erbB-2 variant (ERBB2) mRNA, partial cds. BD404064 - WO 2003091433-A/35: Expression system for stem-loop shaped RNA molecules conferring RNAi. DD115630 - Expression system for stem-loop shaped RNA molecules conferring RNAi. CQ873738 - Sequence 157 from Patent WO2004076622. DD413575 - Regulation of Mammalian Cells. JD188913 - Sequence 169937 from Patent EP1572962. JD102675 - Sequence 83699 from Patent EP1572962. JD205551 - Sequence 186575 from Patent EP1572962. JD547356 - Sequence 528380 from Patent EP1572962. JD168751 - Sequence 149775 from Patent EP1572962. JD185678 - Sequence 166702 from Patent EP1572962. JD282690 - Sequence 263714 from Patent EP1572962. JD403813 - Sequence 384837 from Patent EP1572962. JD331200 - Sequence 312224 from Patent EP1572962. JD384296 - Sequence 365320 from Patent EP1572962.
Biochemical and Signaling Pathways
BioCarta from NCI Cancer Genome Anatomy Project h_her2Pathway - Role of ERBB2 in Signal Transduction and Oncology h_tffPathway - Trefoil Factors Initiate Mucosal Healing