Human Gene ARMH1 (ENST00000458657.6_5) from GENCODE V47lift37
  Description: Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6PIY5-1; Sequence=Displayed; Name=2; IsoId=Q6PIY5-2; Sequence=VSP_031683; (from UniProt Q6PIY5)
Gencode Transcript: ENST00000458657.6_5
Gencode Gene: ENSG00000198520.12_16
Transcript (Including UTRs)
   Position: hg19 chr1:45,140,385-45,191,263 Size: 50,879 Total Exon Count: 13 Strand: +
Coding Region
   Position: hg19 chr1:45,155,370-45,191,075 Size: 35,706 Coding Exon Count: 11 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:45,140,385-45,191,263)mRNA (may differ from genome)Protein (440 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblExonPrimerGeneCardsMGIPubMed
UniProtKB

-  Comments and Description Text from UniProtKB
  ID: CA228_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C1orf228; AltName: Full=p40;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 13.09 RPKM in Testis
Total median expression: 79.09 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -102.00307-0.332 Picture PostScript Text
3' UTR -73.90188-0.393 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR011989 - ARM-like
IPR016024 - ARM-type_fold

Pfam Domains:
PF17741 - Family of unknown function (DUF5578)

SCOP Domains:
48371 - ARM repeat
48431 - Lipovitellin-phosvitin complex, superhelical domain

ModBase Predicted Comparative 3D Structure on Q6PIY5
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  JD280771 - Sequence 261795 from Patent EP1572962.
JD221546 - Sequence 202570 from Patent EP1572962.
BC026115 - Homo sapiens chromosome 1 open reading frame 228, mRNA (cDNA clone MGC:33556 IMAGE:4822241), complete cds.
JD281169 - Sequence 262193 from Patent EP1572962.
JD331298 - Sequence 312322 from Patent EP1572962.
CU693138 - Synthetic construct Homo sapiens gateway clone IMAGE:100022655 5' read MGC33556 mRNA.
KJ904196 - Synthetic construct Homo sapiens clone ccsbBroadEn_13590 C1orf228 gene, encodes complete protein.
AY254217 - Homo sapiens p40 mRNA, complete cds.
JD080791 - Sequence 61815 from Patent EP1572962.
JD399405 - Sequence 380429 from Patent EP1572962.
JD142708 - Sequence 123732 from Patent EP1572962.
JD290003 - Sequence 271027 from Patent EP1572962.
JD191701 - Sequence 172725 from Patent EP1572962.
JD393745 - Sequence 374769 from Patent EP1572962.
JD324759 - Sequence 305783 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A1KXE5, ARMD1_HUMAN, ARMH1 , BC026115, C1orf228, ENST00000458657.1, ENST00000458657.2, ENST00000458657.3, ENST00000458657.4, ENST00000458657.5, NCRNA00082, Q6PIY5, uc320zlh.1
UCSC ID: ENST00000458657.6_5
RefSeq Accession: NM_001145636.2
Protein: Q6PIY5 (aka CA228_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.